tag:blogger.com,1999:blog-1732132352927731247.post5906350122646835614..comments2024-03-16T00:27:31.848-07:00Comments on Hooked: Ethics, Medicine, and Pharma: How Commerce Reshapes Knowledge: Matheson on Pharma's Influence on ScienceHoward Brodyhttp://www.blogger.com/profile/00599587504924835039noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-1732132352927731247.post-53989606538519915742010-11-27T13:22:43.115-08:002010-11-27T13:22:43.115-08:00Howard, here is a link to Alastair Matheson's ...Howard, here is a link to Alastair Matheson's article (no subscription required) via his website www.admatheson.com:<br /> <br />http://tinyurl.com/2cojb9mNancy Wilsonhttps://www.blogger.com/profile/00094553230235804728noreply@blogger.comtag:blogger.com,1999:blog-1732132352927731247.post-22884440330715927352010-11-26T21:24:06.515-08:002010-11-26T21:24:06.515-08:00One powerful driver of the emphasis on pharmaceuti...One powerful driver of the emphasis on pharmaceuticals is the "need" for a placebo-controlled study.<br /><br />Since pharmaceuticals are about the only intervention for which a placebo is possible, that "need" for a placebo control delegitimizes other types of interventions, especially social or educational interventions.<br /><br />Furthermore the conflation of statistical significance with clinical significance encourages investigators to pursue lines of research which are clinically useless.Joseph P. Arpaia, MDnoreply@blogger.com