tag:blogger.com,1999:blog-1732132352927731247.post5127246661104844051..comments2024-03-16T00:27:31.848-07:00Comments on Hooked: Ethics, Medicine, and Pharma: NEJM: Overly Defensive, or Just Naive?Howard Brodyhttp://www.blogger.com/profile/00599587504924835039noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-1732132352927731247.post-50148611929457976062012-10-10T19:53:06.969-07:002012-10-10T19:53:06.969-07:00We could not afford to make mistakes especially if...We could not afford to make mistakes especially if it deals about life and how serious it is. There are certain circumstances here in our planet that we need to practice perfection even though there is no such thing like perfect, but at least strive to have it. Lesser mistakes is better.Anti Money Launderinghttp://aml-assassin.comnoreply@blogger.comtag:blogger.com,1999:blog-1732132352927731247.post-78475247796998093842012-10-09T08:02:17.114-07:002012-10-09T08:02:17.114-07:00"Sildenafil Citrate" is obviously just t..."Sildenafil Citrate" is obviously just trying to sell erection drugs, so normally I'd have deleted that comment, but I left it up as it gives me a chance to reinforce the main point. That blogger notes that one of the criteria that should guide assessment of the trial's validity is "fairness of results reporting"-- not funding source. That's exactly the issue. How do we know whether results are reported fairly unless we could see the trial's raw data, which no journal reader ever can? This blog is full of examples of industry-funded studies where reported results are skewed toward the marketing message, in ways the average journal reader could never find out.Howard Brodyhttps://www.blogger.com/profile/00599587504924835039noreply@blogger.comtag:blogger.com,1999:blog-1732132352927731247.post-73174020899146039152012-10-09T06:01:47.140-07:002012-10-09T06:01:47.140-07:00A trial's validity should ride on the study de...A trial's validity should ride on the study design, the quality of data-accrual and analytic processes, and the fairness of results reporting. Ideally, these factors — not the funding source. There are lot of things which will undergo in hospital. Sildenafil Citratehttp://www.shop4allrx.com/noreply@blogger.comtag:blogger.com,1999:blog-1732132352927731247.post-29431851375327505412012-09-29T11:41:27.743-07:002012-09-29T11:41:27.743-07:00You asked: “The real question is: when are we goin...You asked: “The real question is: <b>when are we going to demand that truly "informed consent" for research subjects in industry-sponsored trials include disclosure of when the trial is not designed for scientific purposes and is instead designed for drug marketing purposes?”</b> The term for such a study is <b>experimercial</b>.Bernard Carrollhttps://www.blogger.com/profile/16203083806436919715noreply@blogger.comtag:blogger.com,1999:blog-1732132352927731247.post-43171171908956619742012-09-29T06:12:16.438-07:002012-09-29T06:12:16.438-07:00Howard,
Thanks for an excellent post. Human subje...Howard,<br /><br />Thanks for an excellent post. Human subjects are not being well informed and I suspect that at least some would be more wary of participating if they knew a study was industry sponsored. Shannon Brownleenoreply@blogger.comtag:blogger.com,1999:blog-1732132352927731247.post-52629106042772691282012-09-27T23:24:47.520-07:002012-09-27T23:24:47.520-07:00Remember when Merck failed to report a few heart a...Remember when Merck failed to report a few heart attacks which occurred during a clinical trial... in an article published in NEJM? Drazen was not the editor then, but still this incidence of covering up negative data is well-known. Anonymousnoreply@blogger.com